Glycine is a classical neurotransmitter that has role in both inhibitory and excitatory synapses. Glycinergic neuron is a neural cell that utilize glycine as a neurotransmitter. Glycinergic neurons are major contributors to the regulation of neuronal excitability, mainly in caudal areas of the nervous system. These neurons control fluxes of sensory information between the periphery and the CNS and diverse motor activities like locomotion, respiration or vocalization. The phenotype of a glycinergic neuron is determined by the expression of at least two proteins: GlyT2, a plasma membrane transporter of glycine, and VIAAT, a vesicular transporter shared by glycine and GABA.
Sodium- and chloride-dependent glycine transporter 2, also known as glycine transporter 2 (GlyT2), is a membrane protein which recaptures glycine. GlyT2 is a specific marker of glycinergic neurons and a member of the Na+ and Cl−-coupled transporter family SLC6.
| Cat. No | Product Name | Reactivity | Application |
| DPAB-DC3740 | Anti-SLC6A5 (aa 294-393) polyclonal antibody | H | WB, ELISA |
| DCABH-4642 | Anti-SLC6A5 monoclonal antibody, clone FQS21859 | H, M, R | WB |
Sodium- and chloride-dependent glycine transporter 1, also known as glycine transporter 1, is a glycine transporter that is present in forebrain areas where it terminates glycine activity by mediating its uptake. GlyT1 is associated with both glycinergic and glutamatergic pathways, and is the main regulator of the glycine levels in the synapses. It has been implicated in diseases such as schizophrenia.
| Cat. No | Product Name | Reactivity | Application |
| DCABH-16900 | Anti-SLC6A9 monoclonal antibody | H | WB, ELISA |
| DPABH-13074 | Anti-SLC6A9 (aa 11-60) polyclonal antibody | H, M, R | WB |
Vesicular inhibitory amino acid transporter is a membrane protein which is involved in gamma-aminobutyric acid (GABA) and glycine uptake into synaptic vesicles. It is localized in synaptic vesicles of glycinergic as well as GABAergic neurons.
| Cat. No | Product Name | Reactivity | Application |
| DPAB2403RH | Anti-SLC32A1 (C-terminal) polyclonal antibody | H | IF |
Species: H Human; M Mouse; R Rat; Z Zebrafish; X Xenopus laevis; B Bovine; C Cow; D Dog; P Pig; Q Quail
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