Bergmann glial cells play critical roles in the structure and function of the cerebellum. During development, their radial processes serve as guides for migrating granule neurons and their terminal endfeet tile to form the glia limitans. As the cerebellum matures, Bergmann glia perform important roles in synaptic transmission and synapse maintenance, while continuing to serve as essential structural elements. The glial genes, Slc1a3, Fabp7, S100β and Sept4 are four widely used astroglial markers, and their expression in Bergmann glia (but not Purkinje cells or other cerebellar neurons) has been confirmed by previous studies.
BLBP is a protein involved in lipid metabolism and membrane synthesis. Its expression has been related with the neurogenic and/or gliogenic potential of radial glia. Some studies have referred to BLBP expression in the embryonic and adult brain in non-mammalian vertebrates. This protein has been detected in RGCs in the telencephalon of amphibian embryos and adult zebrafish. However, BLBP does not allow to clearly distinguish RGCs from NECs since it is expressed by both cell types.
| Cat. No | Product Name | Reactivity | Application |
| DCABH-2449 | Anti-FABP7 monoclonal antibody, clone BU2E2 | H, M | WB, IHC-P |
| DCABH-11484 | Anti-FABP7 monoclonal antibody, clone 2I9 | H | WB, ELISA |
| DPABH-09364 | Anti-Human FABP7 monoclonal antibody | H | IHC, WB |
Glial fibrillary acidic protein (GFAP) is considered to be a highly specific marker for glia. It is a type III intermediate filament (IF) protein that is expressed by numerous cell types of the central nervous system (CNS), including astrocytes and ependymal cells during development.
| Cat. No | Product Name | Reactivity | Application |
| DPABH-19078 | Anti-GFAP polyclonal antibody | H, R | WB, ELISA, IHC-P, ICC/IF |
| CPBT-66669GH | Anti-GFAP (C-terminal) polyclonal antibody | H, M, R, D | WB, ELISA |
| CABT-BL8484 | Anti-GFAP (C-terminal) monoclonal antibody, clone SN393 | H, M | IHC, WB |
SOX2, a HMG box transcription factor, a persistent marker for multipotential neural stem cells derived from embryonic stem cells, the embryo or the adult. SOX2 belongs to the family of SOXB1 factors and is a pivotal regulator of maintenance and induction of both PSCs and neural progenitor cells.
| Cat. No | Product Name | Reactivity | Application |
| DMABT-H23512 | Anti-SOX2 monoclonal antibody, clone Cukdf | H | FC, ELISA, IHC-P, ICC, WB |
| DCABH-2131 | Anti-SOX2 monoclonal antibody, clone 4B3 | H | WB, ELISA, IHC-P |
| DCABH-5662 | Anti-SOX2 monoclonal antibody, clone 31H6 | H, M | IHC-P, IP, WB, FC, ICC/IF |
S100 calcium-binding protein B (S100B) is a protein of the S-100 protein family. S100 proteins are localized in the cytoplasm and nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100B has emerged as a candidate peripheral biomarker of blood–brain barrier (BBB) permeability and CNS injury.
| Cat. No | Product Name | Reactivity | Application |
| DMABT-H27120H | Anti-S100B monoclonal antibody, clone TD68-13 | H, M, R, G, Z | WB, ICC/IF, IP, IHC |
| CABT-12099MH | Anti-S100B monoclonal antibody, clone 2C3 | H | WB, IHC, ELISA |
| DCABH-13354 | Anti-S100B monoclonal antibody, clone 2B20 | H | WB, ELISA |
Nerve growth factor receptor p75NTR is a major neurotrophin receptor involved in manifold and pleiotropic functions in the developing and adult central nervous system (CNS). Depending on the complex interactions with other receptors and on the cellular context, p75NTR is capable of performing contradictory tasks such as mediating cell death as well as cell survival. In parallel, as a prototype marker for certain differentiation stages of Schwann cells and related CNS aldynoglial cells, p75NTR has recently gained increasing notice as a marker for cells with proposed regenerative potential in CNS diseases, such as demyelinating disease and traumatic CNS injury.
| Cat. No | Product Name | Reactivity | Application |
| DCABH-6184 | Anti-P75 NGF Receptor monoclonal antibody, clone 6D5C0 | M | WB |
The glutamate transporter GLAST is localized on the cell membrane of mature astrocytes and is also expressed in the ventricular zone of developing brains. Reports show that the glutamate transporter GLAST is expressed from radial glia through astrocytes during spinal cord development.
| Cat. No | Product Name | Reactivity | Application |
| DCABH-7305 | Anti-SLC1A3 monoclonal antibody, clone 3H8d3 | R | WB, IHC, ELISA |
| DPABH-27425 | Anti-Human SLC1A3 polyclonal antibody | H, M, R | WB, IP, IHC, IF, ELISA |
| DPABH-02585 | Anti-Human SLC1A3 polyclonal antibody | H, M, R | WB |
Species: H Human; M Mouse; R Rat; Z Zebrafish; X Xenopus laevis; B Bovine; C Cow; D Dog; P Pig; Q Quail; G Goat
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