Anti-SLC6A5 (aa 294-393) polyclonal antibody

Species Reactivity

Human

Immunogen

SLC6A5 (NP_004202, 294 a.a. ~ 393 a.a) partial recombinant protein with GST tag. The sequence is TLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVISDHPKIQIKNSTFCMTAYPN VTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIR

Conjugate

Alternative Names

SLC6A5; solute carrier family 6 (neurotransmitter transporter), member 5; NET1; GLYT2; HKPX3; GLYT-2; sodium- and chloride-dependent glycine transporter 2; glycine transporter 2; solute carrier family 6 (neurotransmitter transporter, glycine), member 5;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a sodium- and chloride-dependent glycine neurotransmitter transporter. This integral membrane glycoprotein is responsible for the clearance of extracellular glycine during glycine-mediated neurotransmission. This protein is found in glycinergic axons and maintains a high presynaptic pool of neurotransmitter at glycinergic synapses. Mutations in this gene cause hyperekplexia; a heterogenous neurological disorder characterized by exaggerated startle responses and neonatal apnea.

Pathway

Na+/Cl- dependent neurotransmitter transporters; Transmembrane transport of small molecules;