An axon, or nerve fiber (or nerve fibre: see spelling differences), is a long, slender projection of a nerve cell, or neuron. An axon typically develops side branches called axon collaterals, so that one neuron can send information to several others. These collaterals, just like the roots of a tree, split into smaller extensions called terminal branches. Each of these has a synaptic terminal on the tip. The function of the axon is to transmit information to different neurons, muscles, and glands. Axon dysfunction has caused many inherited and acquired neurological disorders which can affect both the peripheral and central neurons.
L1CAM is a member of the immunoglobulin superfamily of cell adhesion molecules, which has been described to be involved in diverse processes at different stages during development of the nervous system, including regulation of axonal outgrowth, fasciculation, formation of the ventricular system and myelination. L1CAM is specifically localized to axons.
| Cat. No | Product Name | Reactivity | Application |
| DCABH-418 | Anti-L1CAM monoclonal antibody, clone 4H2 | H | WB, IHC-P, FC, ICC/IF |
| DPABH-21764 | Anti-L1CAM (aa 1153-1182) polyclonal antibody | M | WB, ICC/IF, IHC-P |
| CABT-L3782 | Anti-Human L1CAM (Phospho-Ser1181) polyclonal antibody | H, M, R | WB, ELISA |
SCG10 is a developmentally regulated neuronal growth-associated protein, expressed at high levels during neurogenesis, and at low but detectable levels in adulthood. It is expressed in adult sensory neurons, is an efficient and selective marker for regenerating sensory axons in the early stage of axonal regeneration.
| Cat. No | Product Name | Reactivity | Application |
| DPAB-DC348 | Anti-STMN2 (aa 1-90) polyclonal antibody | H | WB, ELISA |
| DPABH-05032 | Anti-STMN2 (aa 2-11) polyclonal antibody | H | WB, IHC-P, ELISA |
| DPABH-28200 | Anti-STMN2 (C-terminal) polyclonal antibody | H, M, R | WB, ICC/IF, IHC |
Neurofilaments are critical for radial axon growth and determine axon caliber, serving as markers for neuronal axons.
| Cat. No | Product Name | Reactivity | Application |
| DMAB5045 | Anti-Neurofilament Protein monoclonal antibody, clone 3G12 | H | FC |
| DMAB6628 | Anti-Neurofilament monoclonal antibody, clone O22-9-5 | B | IHC-P |
βIII-tubulin (TUBB3 or TuJ1) acts as a building block of microtubules, making them fundamental to the cytoskeleton and roles such as cell structure maintenance, meiosis, mitosis, and intracellular transport.
| Cat. No | Product Name | Reactivity | Application |
| DCABH-2322 | Anti-TUBB3 monoclonal antibody, clone 3F0 | H | WB, FC, ICC/IF |
| DCABH-9080 | Anti-TUBB3 monoclonal antibody, clone FQ2670Z | H, M, R, Z | WB, IP, ICC, FC, IHC-P |
| DCABH-17288 | Anti-TUBB3 monoclonal antibody, clone 3F00 | H | WB, IF, ELISA, FC |
Tau proteins are proteins that perform the function of stabilizing microtubules. These proteins are abundant in nerve cells and are present to a much lesser degree in oligodendrocytes and astrocytes. Therefore, Tau proteins are also as a mature neural marker. In addition, it is also a markers for the early diagnosis of Alzheimer's disease (AD).
| Cat. No | Product Name | Reactivity | Application |
| DPABH-13578 | Anti-Human Tau polyclonal antibody | H | WB, IHC, ICC/IF |
| DPABH-28964 | Anti-Tau (Phospho S416) polyclonal antibody | M, R | WB |
| DCABH-9990 | Anti-Tau (Phospho S199) monoclonal antibody, clone FQS3512Z | H, M, R | WB |
Species: H Human; M Mouse; R Rat; Z Zebrafish; X Xenopus laevis; B Bovine; C Cow; D Dog; P Pig; Q Quail; G Goat; Ch Chicken
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