Zebrafish is an emerging immune model used in areas ranging from drug testing to cancer research due to their striking genomic similarity to humans, regenerative abilities and shortened life cycle. Creative diagnostics is now proud to offer a comprehensive and rigorously validated collection of antibodies validated in zebrafish samples. The in-demand 'zebrafish' antibodies are expected to contribute to immune studies.
Our team decided to produce antibodies against key immune molecules in zebrafish to enhance the research within the fish scientific community as well as mammalian immune disorders researches. The currently offered antibodies are for research use only and have been tested on zebrafish samples in various applications.
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Benefits of the Zebrafish
Rapid Embryological Development
Comparing to other vertebrates, zebrafish produce hundreds of eggs at weekly intervals and they grow at an extremely fast rate, developing as much in a day as a human embryo develops in one month.
Fully Sequenced Genome
Animal Models of Human Disease
Permeable, Transparent and Manipulation-Friendly Embryos
Multi-genic screening of target genes
Inject plasmids harboring gene of interests into embryos and monitor the accelerated tumor onset in adult fish.
Modeling metastatic behavior
Tumor metastasis can be followed through the injection of GFP-labelled cell cultures in transparent zebrafish.
Epigenetic mechanisms Studies
One method of studying cancer epigenetics in fish is to perform ChIP upon FACs sorted embryos followed by sequencing or expression profiling.
Chemical libraries can be screened for activity in live zebrafish embryos using early embryonic phenotypic markers in 96 well plates. Toxicity can also be addressed in parallel during the same screening.