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Polyclonal antibody (pAb) is a group of immunoglobulins derived from plasmocyte secretion following the activation of heterologous antigen (macromolecular antigen, hapten conjugate). These antibodies recognise and bind to numerous epitopes of one antigen and hence can engage in lattices with the antigens and precipitate reaction. pAbs are used for different analyses, diagnostics and therapeutic purposes.
Creative Diagnostics provides broad portfolio of pAbs includes 1,000s of targets to support your project. Our pAbs are used in many applications including WB, flow cytometry, ELISA, IHC, and IF.
Find the right antibody from Creative Diagnostics
Creative Diagnostics also offer high quality secondary polyclonal antibody products.
Non-Fluorescent Conjugates
The clinical judgment in treating snakebite comes down to choosing the correct antivenom and dose, based on snake species identification. Immunoassays such as ELISA measure and characterize particular venom, verifying snake identification and prescribing antivenom. Additionally, measuring free venom in the patient after treatment helps assess if sufficient antivenom was administered. Immunoassays can also evaluate the cross-reactivity of different antivenoms.
We offer a variety of polyclonal antibodies against snake venom, and you can browse more related products here.
| Targets | Cat. No. | Product Name | |
| Vipera Venom | DPAB-JX2371341 | Sheep Anti-Vipera l atastei Venom Polyclonal Antibody | Inquiry |
| Pseudechis Venom | DPAB-JX2371312 | Sheep Anti-Pseudechis Venom Polyclonal Antibody | Inquiry |
| Oxyuranus Venom | DPAB-JX2371311 | Sheep Anti-Oxyuranus Venom Polyclonal Antibody | Inquiry |
| Notechis Venom | DPAB-JX2371336 | Sheep Anti-Notechis Venom Polyclonal Antibody | Inquiry |
| Leiurus Venom | DPAB-JX2371330 | Sheep Anti-Leiurus quinquestriatus Venom Polyclonal Antibody | Inquiry |
| Echis Venom | DPAB-JX2371338 | Sheep Anti-Echis pyramidum Venom Polyclonal Antibody | Inquiry |
| Crotalus Venom | DPAB-JX2371317 | Sheep Anti-Crotalus horridus Venom Polyclonal Antibody | Inquiry |
1. Antigen and Adjuvant Preparation
2. Animal Selection
3. Immunization
4. Serum Collection
5. Antibody Purification
6. Quality Control
As a specialized manufacturer in this sector, we have an edge over the rest in the low price of antibody manufacturing. Creative Diagnostics offer a complete antibody production solution to international clients, according to the customer's requirements.
| Monoclonal Antibodies (mAbs) | Polyclonal Antibodies (pAbs) | |
| Origin | Derived from a single clone of B cells | Produced by multiple B cell clones |
| Specificity | High specificity for a single epitope | Broad specificity, recognizing multiple epitopes |
| Production Time | Longer (typically 6+ months) | Shorter (typically 3-4 months) |
| Cost | Generally higher | Generally lower |
| Consistency | High batch-to-batch consistency | Variable between batches |
| Purity | High purity | Lower purity |
| Applications | Suitable for targeted therapies and diagnostics | Versatile for research, diagnostics, and treatment |
| Sensitivity | More sensitive in quantification assays | Higher sensitivity due to multiple binding sites |
| Cross-reactivity | Low cross-reactivity | Higher potential for cross-reactivity |
ELISA tests for viral infections
Snake antivenoms for envenomation treatment
Combining therapeutic cancer vaccines with polyclonal antibodies
Western blotting for protein detection
Flow cytometry to analyze immune cell populations
IF to visualize protein expression
It's usually isolated by serum extraction, followed by protein A or G affinity chromatography separation of the target antibodies from the rest of the serum.
Adjuvants are agents in vaccines that bolster the immune system. They enhance a larger antibody response when the antigen is injected into the animal.
There are immunogenicity, cross-reactivity, easy handling and the amount of serum that can be extracted from the species.
Usually, researchers can verify specificity by WB or ELISA, to ensure that the antibody reacts only with the target protein and doesn’t react with other proteins.
Creative Diagnostics is a "One stop" antibody solutions provider serving the pharmaceutical, biotech, diagnostic and university research organizations around the world.
Tell us how we can support your project
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