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Creative Diagnostics have been dedicating to continuously produce anti-small molecule RHATM Mouse mAbs with highest sensitivity and specificity, which are involved in:
Small molecules, including chemical drugs, metabolites, pesticides, and toxins, are essential targets in pharmaceutical research, clinical diagnostics, food safety, and environmental analysis. However, their low molecular weight and lack of immunogenicity make them inherently difficult to detect.
We provide a comprehensive portfolio of small molecule (hapten) antibodies designed for high specificity, sensitivity, and reproducibility across a wide range of immunoassay platforms.

Quickly navigate our catalog by target type:
Modern biologics carry non-protein components that determine their potency and clearance, a cytotoxic payload, a PEG chain, a chelating group, and every one of them is a hapten. Creative Diagnostics supplies anti-payload and anti-PEG antibodies together with matched conjugates and finished kits, supporting conjugated and free payload measurement and PEGylation assessment. The same reagents underpin our ADC bioanalysis services, so programs can move between buying reagents and outsourcing the assay without changing materials.
Examples: DXd, MMAE, SN-38, PEG, DOTA.
Explore Biopharma Characterization Antibodies
Steroid hormones present a distinctive challenge for immunoassay development. Closely related analytes can share highly conserved molecular structures while circulating at very different concentrations in biological samples. Accurate measurement therefore depends on selecting antibodies with the appropriate combination of specificity, affinity, and cross-reactivity for the intended analyte and assay format. Creative Diagnostics offers antibodies targeting a broad range of endocrine analytes, including reproductive, adrenal, and vitamin D-related targets, with products supporting ELISA, LFIA, CLIA, and other assay development applications.
Examples: Estradiol, Estrone, Cortisol, Aldosterone, DHEA-S, 17-OH-Progesterone, 25-OH Vitamin D.
Explore Steroid Hormones and Endocrine Antibodies
The most commonly used method for current TDM involves immunological assays. Commercial kits are mostly appreciated for their rapidity. Creative Diagnostics provides highly sensitive and cost-effective therapeutic drug conjugates and antibodies for multiple applications. We also offer customized services, which can asset customers to achieve their immunoassay development.
Examples: Digoxin, Methotrexate, Carbamazepine, Gentamicin.
Explore Therapeutic Drug Antibodies
Food safety and environmental monitoring increasingly rely on immunological assays due to their high sensitivity, specificity, and rapid detection capabilities. Creative Diagnostics provides a comprehensive range of high-quality antibodies and conjugates targeting food safety and environmental contaminants, including pesticides, veterinary drug residues, toxins, pollutants, and other small molecules. Our products are designed to support multiple immunoassay platforms and help customers achieve reliable, cost-effective detection solutions.
Examples: Pesticides, Mycotoxins, Veterinary drug residues.
Explore Food & Environmental Antibodies
Drugs of abuse (DOA) testing plays a vital role in workplace screening, clinical toxicology, pain management, forensic analysis, and point-of-care diagnostics. Immunological assays remain the preferred approach for rapid, sensitive, and cost-effective detection of abused drugs and their metabolites. Creative Diagnostics provides a comprehensive portfolio of high-quality antibodies, antigens, and hapten conjugates for a broad range of DOA targets, supporting lateral flow assays, ELISA, CLIA, and other immunoassay platforms. Our products help customers develop reliable and high-performance drug screening assays.
Examples: THC, Morphine, Cocaine, Methamphetamine, Amphetamine, Fentanyl, Methadone, EDDP.
Explore Drugs of Abuse Antibodies
Essential reagents for assay signal generation
Examples: FITC, FAM, DIG, Biotin-related molecules
Small molecules (typically<1 kDa) are non-immunogenic and require conjugation to carrier proteins to elicit antibody production. The performance of anti-hapten antibodies is highly dependent on rational design and preparation strategies.
We optimize every stage of antibody development to deliver high-performance reagents:
Our antibodies are designed not only for binding, but for real world assay integration.
Our antibodies are engineered to support:
This enables reliable performance from early-stage research to commercial assay development.
Explore some of our widely used products:

Key features and details

ELISA binding of CABT-L3115 with SN38

The antibody affinity curves of CABT-B8992 with MMAE
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