Hirudin prevents or dissolves the formation of clots and thrombi, and has therapeutic value in blood coagulation disorders, in the treatment of skin hematomas and of superficial varicose veins. Recombinant hirudin (r-hirudin or lepirudin) not only provides effective anticoagulation in patients with heparin-induced thrombocytopenia (HIT) but also allows rapid platelet recovery.
Tuberculosis (TB) is a contagious and often severe airborne disease caused by infection with Mycobacterium tuberculosis bacteria. TB usually affects the lungs, but can also affect other parts of the body.
Compared to traditional indirect assays, the double-antigen sandwich ELISA displays higher specificity and better sensitivity. With years of experience in production of proteins and antigens, Creative Diagnostics now can provide our customers matched antigen pairs of HCV with high-quality and cheaper price for the development of double-antigen sandwich ELISA.
Helicobacter pylori (H. pylori), a powerful carcinogenic pathogen, is responsible for the induction of 75% of gastric cancers worldwide. In general, the current treatment for patients who are infected with H. pylori consists of daily administration of three antibiotics, proton pump inhibitor, amoxicillin, clarithromycin.
The Omicron variant, with a large number of spike gene mutations was designated a variant of concern (VOC). There is still considerable uncertainty related to the transmissibility, vaccine effectiveness, severity of infection and other properties of the Omicron variant.
Viruses are infectious pathogens that cause a broad range of diseases. They are small particles, typically between 20 and 300 nanometers in length, containing RNA or DNA. Viruses require a host cell to replicate.
Infectious diseases continue to be a major threat to human health. Factors that contribute to this include the changes in life style such as the increasing migration, the rising resistance of pathogens to antibiotherapy and the increasing number of immunosuppressed patients.
The name "influenza" is derived from the Latin word for "influence," and the pathogens that cause this disease are RNA viruses from the family Orthomyxoviridae.
An allergen is a type of antigen that produces an abnormally vigorous immune response in which the immune system fights off a perceived threat that would otherwise be harmless to the body. Such reactions are called allergies.
Tumor markers can be defined as some substances produced by the tumor or by the body in response to the tumor. These markers are either produced by tumor cells (tumor-derived) or by the body in response to tumor cells (tumor-associated).
The Mouse SARS-CoV-2 IgG1 & IgG2a ELISA kit developed by Creative Diagnostics can help evaluate the type of immune response induced by the COVID-19 vaccine in mouse.
Creative Diagnostics provides a panel of highly sensitive antibiotics ELISA kits to analyze antibiotic residues. These kits are suitable as good impurity detection tools to be used in the bioproduction process.
The Anti-PEG Assay Kits manufactured by Creative Diagnostics, Inc. allows measurement of the anti-PEG antibodies in species who have absorbed PEGylated drugs or proteins, and are suitable for evaluating the pharmacodynamics of candidate drugs.
Creative Diagnostics has developed a panel of recombinant RBD/Spike and nucleocapsid protein variants which can be used to evaluate the efficacy of the antibodies and vaccination.
Creative Diagnostics has developed anti-MMAE antibodies and paired conjugates that are suitable for ADC ELISA assay development.
CD offers a variety of VSV vectors pseudotyped with SARS-CoV-2 Spike proteins. Different products can be used to express different reporters such as EGFP or luciferase, allowing the tracking of viral entry into host cells by a variety of assays.
The SARS-CoV-2 spike CHO-K1 cell line has been developed by stable transfection with SARS-CoV-2 spike protein expression plasmid. SARS-CoV-2 spike CHO-K1 cell line provides consistent levels of expression of SARS-CoV-2 spike protein in cells surface.
Creative Diagnostics has developed a series of functional grade recombinant chimeric antibodies. These antibodies are well-validated in comprehensive applications including Agonism, Blocking, Depletion, Neutralization, WB, IP, FC, and IHC. The newly launched antibodies consist of a series of most popular recombinant mouse anti-mouse antibodies ideal for in vivo research in mouse models.
Creative Diagnostics has recently developed several CLDN18.2 antibodies. The antibodies were validated and characterized by multiple applications with high specificity and affinity.
Immunogenicity assessments in vaccine trials have focused on measurements of antibody responses to the vaccine. Creative Diagnostics has launched a full series of HPV reporter virus particles for measuring neutralizing anti-HPV antibodies in a pseudovirion-based neutralization assay (PBNA).