Recombinant HSV type 2 VP22

Product Overview

The E.Coli derived Full length HSV-2 VP22 recombinant protein is fused to a Six histidine tag at C-terminus and has a MW of 33,5kDa (pI 10.5).

Nature

Recombinant

Tag/Conjugate

Unconjugated

Molecular Weight

33,5kDa

Alternative Names

HSV; Herpesviruses; Herpesviridae; Herpes Simplex Virus Type 2; HSV type 2 VP22

Purity

Protein is>90% pure as determined by SDS PAGE.

Format

Sterile Filtered clear solution.

Concentration

Batch dependent - please inquire should you have specific requirements.

Buffer

10 mM Phosphate buffer pH 7.6; 75 mM NaCl.

Preservative

None

Storage

HSV-2 VP22 although stable at 4°C for 1 week, should be stored below -18°C.
Please prevent freeze thaw cycles.

Antigen Description

Entry of HSV into the host cell involves interactions of several viral glycoproteins with cell surface receptors. The virus particle is covered by an envelope which, when bound to specific receptors on the cell surface, will fuse with the cell membrane and create an opening, or pore, through which the virus enters the host cell. The sequential stages of HSV entry are analagous to those of other viruses. At first, complementary receptors on the virus and cell surface bring the two membranes into proximity. In an intermediate state, the two membranes begin to merge, forming a hemifusion state. Finally, a stable entry pore is formed through which the viral envelope contents are introduced to the host cell.

Keywords

HSV;Herpesviruses;Herpesviridae;Herpes Simplex Virus Type 2;HSV type 2 VP22