Product Overview
Purified recombinant ecto-domain of HSV-2 gD
Tag/Conjugate
Unconjugated
Alternative Names
HSV; Herpesviruses; Herpesviridae; Herpes Simplex Virus Type 2; HSV type 2 gD
Purity
SDS-PAGE must demonstrate a major band in the region of 37kDa or comparable to reference lot.
Testing results: Pass
Immunospecificity verified by WB
Concentration
Batch dependent - please inquire should you have specific requirements.
Buffer
20mM Sodium Phosphate, pH 6.8-7.2, 200mM NaCl, 0.1mM EDTA
Storage
Store at -80°C. Avoid repeated freeze/thaw cycles
Antigen Description
Entry of HSV into the host cell involves interactions of several viral glycoproteins with cell surface receptors. The virus particle is covered by an envelope which, when bound to specific receptors on the cell surface, will fuse with the cell membrane and create an opening, or pore, through which the virus enters the host cell. The sequential stages of HSV entry are analagous to those of other viruses. At first, complementary receptors on the virus and cell surface bring the two membranes into proximity. In an intermediate state, the two membranes begin to merge, forming a hemifusion state. Finally, a stable entry pore is formed through which the viral envelope contents are introduced to the host cell.
Keywords
HSV;Herpesviruses;Herpesviridae;Herpes Simplex Virus Type 2;HSV type 2 gD
Citations
Publication ()
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COA
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