Tag/Conjugate
Unconjugated
Alternative Names
HSV; Herpesviruses; Herpesviridae; Herpes Simplex Virus Type 2; HSV type 2 gG
Concentration
Batch dependent - please inquire should you have specific requirements.
Buffer
0.04 M Tris-HCl, containing 3 M MgCl2, pH 7.5
Storage
Store at -65 to -80°C. Avoid multiple freeze/thaw cycles.
Antigen Description
Entry of HSV into the host cell involves interactions of several viral glycoproteins with cell surface receptors. The virus particle is covered by an envelope which, when bound to specific receptors on the cell surface, will fuse with the cell membrane and create an opening, or pore, through which the virus enters the host cell. The sequential stages of HSV entry are analagous to those of other viruses. At first, complementary receptors on the virus and cell surface bring the two membranes into proximity. In an intermediate state, the two membranes begin to merge, forming a hemifusion state. Finally, a stable entry pore is formed through which the viral envelope contents are introduced to the host cell.
Keywords
HSV;Herpesviruses;Herpesviridae;Herpes Simplex Virus Type 2;HSV type 2 gG
Citations
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Heaton, PR; Espy, MJ; et al. Evaluation of 2 multiplex real-time PCR assays for the detection of HSV-1/2 and Varicella zoster virus directly from clinical samples. DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE 81:169-170(2015).
Alekseenko, IV; Snezhkov, EV; et al. Therapeutic properties of a vector carrying the HSV thymidine kinase and GM-CSF genes and delivered as a complex with a cationic copolymer. JOURNAL OF TRANSLATIONAL MEDICINE 13:-(2015).
COA
Certificate of Analysis
