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    Anti-CTLA4 monoclonal antibody

    Mouse anti-Human CTLA4 monoclonal antibody for FC

    Bring this labeled antibody directly to your bench!

    Low Endotoxin/Azide Free CTLA4 antibody available!

    pdf COA pdf SDS pdf Datasheet
    Specifications
    Antibody Isotype
    IgG2a
    Clone
    COJ4
    Species Reactivity
    Human
    Immunogen
    Human CTLA-4/human IgG heavy chain fusion protein (CTLA-4/Ig).
    Conjugate
    Unconjugated
    Applications
    Application Notes
    ICC: 5 - 50 μg/ml; Flow Cyt: 2μg/5x 105 cells; IHC-Fr: 5 - 50 μg/ml;
    Target
    Alternative Names
    CTLA4; cytotoxic T-lymphocyte-associated protein 4; cytotoxic T-lymphocyte protein 4; CD 152; CD; CD152; CD152 antigen; Celiac disease 3; CELIAC3; CTLA 4; CTLA-4; CTLA4; CTLA4_HUMAN; Cytotoxic T cell associated 4; Cytotoxic T lymphocyte associated 4; Cyto
    Entrez Gene ID
    1493
    UniProt ID
    P16410
    Product Background
    Antigen Description
    This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy.
    Pathway
    Adaptive Immune System, organism-specific biosystem; Autoimmune thyroid disease, organism-specific biosystem; Autoimmune thyroid disease, conserved biosystem; CTLA4 inhibitory signaling, organism-specific biosystem; Calcineurin-regulated NFAT-dependent transcription in lymphocytes, organism-specific biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Costimulation by the CD28 family, organism-specific biosystem; Immune Syst
    Custom Antibody Labeling
    We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
    Citations
    Have you cited CABT-28212MH in a publication? Let us know and earn a reward for your research.
    Product Name Cat. No. Applications Host Species Datasheet Price Add to Basket
    Mouse IgG2a Isotype Control DAGIC1216 FC EIA IHC Mouse pdf PDF Inquiry
    Customer Reviews
    Tsai, MK; Ho, HN; et al. The role of B7 ligands (CD80 and CD86) in CD152-mediated allograft tolerance: A crosscheck hypothesis. TRANSPLANTATION 77:48-54(2004).
    Woo, PCY; Lau, SKP; et al. SARS coronavirus spike polypeptide DNA vaccine priming with recombinant spike polypeptide from Escherichia coli as booster induces high titer of neutralizing antibody against SARS coronavirus. VACCINE 23:4959-4968(2005).
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