Anti-CTLA4 monoclonal antibody (CABT-28212MH)

Mouse anti-Human CTLA4 monoclonal antibody for FC, ICC, IHC-Fr Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2a
Clone
COJ4
Species Reactivity
Human
Immunogen
Human CTLA-4/human IgG heavy chain fusion protein (CTLA-4/Ig).
Conjugate
Unconjugated

Applications


Application Notes
ICC: 5 - 50 μg/ml; Flow Cyt: 2μg/5x 105 cells; IHC-Fr: 5 - 50 μg/ml;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
CTLA4; cytotoxic T-lymphocyte-associated protein 4; cytotoxic T-lymphocyte protein 4; CD 152; CD; CD152
Entrez Gene ID
UniProt ID

Product Background


Pathway
Adaptive Immune System, organism-specific biosystem; Autoimmune thyroid disease, organism-specific biosystem; Autoimmune thyroid disease, conserved biosystem; CTLA4 inhibitory signaling, organism-specific biosystem; Calcineurin-regulated NFAT-dependent transcription in lymphocytes, organism-specific biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Costimulation by the CD28 family, organism-specific biosystem; Immune Syst

Citations


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References


Iannone, F; Lapadula, G; et al. The Inhibitor of Costimulation of T Cells: Abatacept. JOURNAL OF RHEUMATOLOGY 39:100-102(2012).
Hu, YH; Sun, BG; et al. Molecular characterization of Cynoglossus semilaevis CD28. FISH & SHELLFISH IMMUNOLOGY 32:934-938(2012).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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