Anti-CTLA4 monoclonal antibody, clone BU5G3

Name: Anti-CTLA4 monoclonal antibody, clone BU5G3
SKU: DCABH-6403
Rating: 5 (1 reviews)

Mouse anti-Human CTLA4 monoclonal antibody for ELISA, WB

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COA

SDS

Datasheet

Summary

Specifications

Antibody Isotype

IgG1

Clone

BU5G3

Species Reactivity

Mouse; Human

Immunogen

Recombinant fragment corresponding to Human CTLA4 aa 36-161 (extracellular). Purified from E.coli. (NP_005202)Sequence: KAMHVAQPAVVLASSRGIASFVCEYASPGKATEVRVTVLRQADSQVTEVC AATYMMGNELTFLDDSICTGTSSGNQVNLTIQGLRAMDTGLYICKVELMY PPPYYLGIGNGTQIYVIDPEPCPDSD Databa

Conjugate

Unconjugated

Applications

Application Notes

ELISA: 1/3000; WB: 1/3000.

Target

Alternative Names

CTLA4; cytotoxic T-lymphocyte-associated protein 4; celiac disease 3 , CELIAC3; cytotoxic T-lymphocyte protein 4; CD; CD28; CD152; GSE; ICOS; CD152 isoform; celiac disease 3; cytotoxic T-lymphocyte antigen 4; cytotoxic T-lymphocyte-associated antigen 4; c

Entrez Gene ID

1493

UniProt ID

P16410

Product Background

Antigen Description

Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.

Pathway

Adaptive Immune System, organism-specific biosystem; Autoimmune thyroid disease, organism-specific biosystem; Autoimmune thyroid disease, conserved biosystem; CTLA4 inhibitory signaling, organism-specific biosystem; Calcineurin-regulated NFAT-dependent transcription in lymphocytes, organism-specific biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem;

Citations