Anti-CTLA4 monoclonal antibody (DMABT-H13536)

Mouse anti-Human CTLA4 monoclonal antibody for EIA, FC Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
BOD263.3/9I6
Species Reactivity
Human
Immunogen
A mixture of stimulated human PBLs and human CTLA4 Ig fusion protein.
Conjugate
Unconjugated

Target


Alternative Names
CTLA4; cytotoxic T-lymphocyte-associated protein 4; celiac disease4, CELIAC3; cytotoxic T-lymphocyte protein 4; CD; CD28
Entrez Gene ID
UniProt ID

Product Background


Pathway
Adaptive Immune System, organism-specific biosystem; Autoimmune thyroid disease, organism-specific biosystem; Autoimmune thyroid disease, conserved biosystem; CTLA4 inhibitory signaling, organism-specific biosystem; Calcineurin-regulated NFAT-dependent transcription in lymphocytes, organism-specific biosystem; Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem;

Citations


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References


Lute, KD; May, KF; et al. Human CTLA4 knock-in mice unravel the quantitative link between tumor immunity and autoimmunity induced by anti-CTLA-4 antibodies. BLOOD 106:3127-3133(2005).
Davies, JK; Barbon, CM; et al. Ex Vivo Alloanergization With Belatacept: A Strategy to Selectively Modulate Alloresponses After Transplantation. CELL TRANSPLANTATION 21:2047-2061(2012).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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