Acidic ionic liquid grafted PPF membrane reactor and its catalytic esterification kinetics
CHEMICAL ENGINEERING JOURNAL
Authors: Zhang, Jun; Zhao, Xin; Wang, Wen-Zhi; Zhao, Zhi-Ping
Abstract
Electrospun polypropylene fibrous (PPF) membrane was selected as a substrate to graft ionic liquids (ILs) and avoid tedious ILs separation and recovery. A catalytic membrane, BILs-g-PPF, was prepared by long-distance and dynamic low-temperature Ar plasma flow activation and subsequent grafting with dual -SO3H imidazole Bronsted acidic ILs (BILs), [(CH2)(3)SO(3)HVIm]HSO4. A novel multistage membrane series reactor was first developed by employing the BILs-g-PPF membrane to catalyze esterification of acetic acid with ethyl alcohol. The BILs, which supplied strong active H+ and benefited to overcome the chemical equilibrium due to its high hydrophilic groups, was chosen as a catalyst. The three-dimensional porous network architecture of PPF membrane provided a high specific surface area to graft considerable BILs and enhanced mass transfer in membrane. The optimization of reaction conditions was studied and the results were as followed: BILs grafting degree of 213.5 mol/m(3), reaction temperature 70 degrees C, molar ratio of acid to alcohol 1:5, membrane flux of 21.36 L/(m(2).h). In single-stage catalytic membrane system, the acid conversion achieved 66.24% in 8 h. The multistage membrane series reactor can improve the reaction conversion efficiency. For the used membrane which lost some anions, its catalytic properties could be largely restored by soaking activation using a dilute sulfuric acid aqueous solution with a mass concentration of 10%. The proposed reaction kinetic models which related the feed volume and membrane structure parameters predict the esterification process well at different conditions.
Ocular vs. Cervical Vestibular Evoked Myogenic Potentials in Benign Paroxysmal Positional Vertigo: A Systematic Review and Meta-Analysis
FRONTIERS IN NEUROLOGY
Authors: Chen, Gang; Dai, Xiaoyan; Ren, Xiuping; Lin, Naifen; Zhang, Min; Du, Zhaolin; Zhang, Endong
Abstract
Objective: To compare utricular dysfunction with saccular dysfunction in benign paroxysmal positional vertigo (BPPV), based on ocular vestibular evoked myogenic potentials (oVEMP) and cervical VEMP (cVEMP), respectively. Materials and Methods: We performed a literature search exploring utricular and saccular dysfunction in BPPV patients through June 2020 using oVEMP and cVEMP, respectively. The databases included Pubmed, Embase, CENTRAL, CNKI, Wan Fang Data, and CBM. The literatures were limited to Chinese and English. Inclusion criteria and exclusion criteria were defined. We adopted abnormal rate as the outcome. All statistical processes were conducted through software Review Manager. Considering the air-conducted sound (ACS) and bone conducted vibration (BCV) may have different mechanisms, and three types of diagnostic criteria for abnormal VEMP were available, sub-group analysis was performed simultaneously according to the sound stimuli and the diagnostic criteria of abnormal VEMP. Results: We retrieved 828 potentially relevant literatures, and finally 12 studies were included for meta-analysis of abnormal rate after duplication removal, titles and abstracts screening, and full-text reading. The abnormal rate of oVEMP was not significantly different from cVEMP (OR = 1.59, 95% CI = 0.99-2.57). But the abnormal rate was obviously different between the subgroups adopting ACS oVEMP and BCV oVEMP. In studies adopting ACS oVEMP, the abnormal rate of oVEMP was higher than cVEMP (OR = 1.85, 95% CI = 1.38-2.49). The abnormal rate of oVEMP was also higher than cVEMP when adopting asymmetry ratio (AR) and no response (NR) as diagnostic criteria (OR = 2.16, 95% CI = 1.61-2.89). Conclusion: The meta-analysis reveals that utricular dysfunction may be more predominant in BPPV compared with saccular dysfunction.