HSV 2-gG (DAGB467)

HSV2-gG, recombinant protein from Insect Cell Datasheet

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Nature
Recombinant
Tag/Conjugate
unconjugated
Alternative Names
HSV2 glycoprotein G
Format
Liquid
Buffer
50 mM Tris, 5 mM DTT, 1 mM EDTA, 0.1% Triton X-100, pH 8.0
Storage
≤ -70°C
Introduction
Entry of HSV into the host cell involves interactions of several viral glycoproteins with cell surface receptors. The virus particle is covered by an envelope which, when bound to specific receptors on the cell surface, will fuse with the cell membrane and create an opening, or pore, through which the virus enters the host cell. The sequential stages of HSV entry are analagous to those of other viruses. At first, complementary receptors on the virus and cell surface bring the two membranes into proximity. In an intermediate state, the two membranes begin to merge, forming a hemifusion state. Finally, a stable entry pore is formed through which the viral envelope contents are introduced to the host cell.
Keywords
Herpes Simplex Virus-2 gG; HSV; HSV2; Herpes Simplex Virus-2; HSV2 glycoprotein G

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