Product Overview
Full-length human tau modified by a C-terminal 6xHis tag and a phosphorylation site at T181.
Molecular Weight
48.3 kDa
Alternative Names
DDPAC; FTDP-17; MAPT; MSTD; MTBT1; Tau; PHF-tau; TAU
Purity
≥80% estimated by SDS-PAGE
Buffer
0.15 M Phosphate buffered saline, pH 7.4
Storage
2 days when stored at 2 to 8°C after thawing. Up to 12 months when aliquoted and stored at -20 to -80°C.
Introduction
Tau is a microtubule-associated protein, which encodes by the MAPT gene that located on chromosome17q21.Tau Promotes microtubule assembly and stability, and might be involved in the establishment andmaintenanceof neuronal polarity. Hyperphosphorylation of the tau protein (tau inclusions, pTau) canresult intheself-assembly of tangles of paired helical filaments and straight filaments, which are involvedinthepathogenesis of Alzheimers disease, frontotemporal dementia, and other tauopathies.
Keywords
DDPAC; FTDP-17; MAPT; MSTD; MTBT1; Tau; PHF-tau; TAU
Citations
Publication ()
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COA
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 monoclonal Antibody, clone FQS3407.jpg)
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