Anti-MAPT monoclonal antibody (CABT-22079MH)

Mouse anti-Human MAPT monoclonal antibody for WB, ELISA Datasheet

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Specifications


Host Species
Mouse
Clone
SC52
Species Reactivity
Human
Immunogen
Native purified human MAPT from Alzheimer"s disease brain.
Conjugate
Unconjugated

Applications


Application Notes
ELISA (1:1000-1:2000); WB (2-5 μg/mL) & The optimal working dilution should be determined by the end user.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
microtubule-associated protein tau; PPND; MTBT1; Neurofibrillary tangle protein; TAU; Paired helical filament-tau
Entrez Gene ID
UniProt ID

Product Background


Pathway
Alzheimer"s disease, organism-specific biosystem; Alzheimer"s disease, conserved biosystem; Apoptosis, organism-specific biosystem; Apoptotic cleavage of cellular proteins, organism-specific biosystem; Apoptotic execution phase, organism-specific biosystem; Caspase-mediated cleavage of cytoskeletal proteins, organism-specific biosystem

Citations


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References


Nakamura, K; Zhou, XZ; et al. Distinct Functions of cis and trans Phosphorylated Tau in Alzheimer's Disease and their Therapeutic Implications. CURRENT MOLECULAR MEDICINE 13:1098-1109(2013).
Schaeffer, EL; De-Paula, VJ; et al. Inhibition of phospholipase A(2) in rat brain decreases the levels of total Tau protein. JOURNAL OF NEURAL TRANSMISSION 118:1273-1279(2011).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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