Active tau PFFs; tau PFF; active tau protein Pre-formed Fibrils; active tau aggregates; microtubule-associated protein tau; MAPT; MAP; microtubule-associated protein; Paired Helical Filament-Tau; Phf-Tau; Neurofibrillary Tangle Protein; G Protein Beta1/Gamma2 Subunit-Interacting Factor 1; Isoform 4; tubulin-associated unit; mouse tau protein; P301S mutant tau; 2N4R tau; Tau441
Purity
≥95%
Format
Liquid
Concentration
Batch dependent - please inquire should you have specific requirements
Buffer
PBS, pH 7.4
Preservative
None
Storage
Store at -80°C
Introduction
Tau protein is a highly soluble microtubule-associated protein (MAP) that is abundant in neurons of the central nervous system and relatively poorly expressed in non-neuronal cells (astrocytes, oligodendrocytes, etc.). One of its main functions is to maintain axonal microtubule stability and ensure normal brain function. The neurofibrillary tangles observed in Alzheimer's disease (AD) and other tau lesions are aggregations of paired helical fibrils composed of hyperphosphorylated tau.
My Review for Mouse Recombinant Tau-441 (2N4R) P301S Mutant Protein Pre-Formed Fibrils
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COA
Publication 
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