Specifications
Immunogen
Synthetic peptide corresponding to Human alpha Synuclein aa 124-134 (phospho S129) conjugated to Keyhole Limpet Haemocyanin (KLH) (Cysteine residue).Sequence: AYEMPSEEGYQ Database link: P37840
Applications
Application Notes
IHC-P: 1/500 - 1/1000.
Target
Alternative Names
SNCA; synuclein, alpha (non A4 component of amyloid precursor); PARK1, PARK4, Parkinson disease (autosomal dominant, Lewy body) 4; alpha-synuclein; alpha synuclein; NACP; PD1; synuclein alpha-140; non A-beta component of AD amyloid; PARK1; PARK4; MGC1109
Product Background
Antigen Description
May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.
Pathway
Alpha-synuclein signaling, organism-specific biosystem; Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Amyloids, organism-specific biosystem; Disease, organism-specific biosystem; EGFR1 Signaling Pathway, organism-specific biosystem; Parkinsons disease, organism-specific biosystem;
Citations
Publication ()
Have you cited DCABH-7907 in a publication?
Let us know and earn a reward for your research.
COA
Loading ......
