Anti-SNCA monoclonal antibody, clone 5E7

Name: Anti-SNCA monoclonal antibody, clone 5E7
SKU: DCABH-8021
Rating: 5 (1 reviews)

Mouse anti-Human SNCA monoclonal antibody for WB, IHC-P, IHC-Fr, ELISA, IHC

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COA

SDS

Datasheet

Summary

Specifications

Antibody Isotype

IgG1

Clone

5E7

Species Reactivity

Mouse; Rat; Human

Immunogen

Recombinant human alpha synuclein, produced in E.coli.

Conjugate

Unconjugated

Applications

Application Notes

IHC-FoFr: 1/300; Flow Cyt: 1μg/10⁶ cells; WB: 1/100 - 1/10000; IHC-P: 1/100 - 1/1000; IHC-Fr: 1/100 - 1/1000.

Target

Alternative Names

SNCA; synuclein, alpha (non A4 component of amyloid precursor); PARK1, PARK4, Parkinson disease (autosomal dominant, Lewy body) 4; alpha-synuclein; alpha synuclein; NACP; PD1; synuclein alpha-140; non A-beta component of AD amyloid; PARK1; PARK4; MGC1109

Entrez Gene ID

6622

UniProt ID

P37840

Product Background

Antigen Description

May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.

Pathway

Alpha-synuclein signaling, organism-specific biosystem; Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Amyloids, organism-specific biosystem; Disease, organism-specific biosystem; EGFR1 Signaling Pathway, organism-specific biosystem; Parkinsons disease, organism-specific biosystem;

Citations