Anti-SNCA monoclonal antibody (DCABH-3379) Knockout Validated

Rabbit anti-Human SNCA monoclonal antibody for WB, IHC-P, FC, IP, ELISA, ICC/IF

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Clone
NKGS2
Species Reactivity
Human, Fruit fly
Immunogen
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive)
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/10000, unpurified: 1/1000.00000 - 1/10000.00000; IHC-P: 1/150, unpurified: 1/15 to 1/300; Flow Cyt: 1/200, unpurified: 1/20; IP: 1/600, unpurified: 1/50; ELISA: 1 - 10 μg/ml; ICC/IF: 1/150, unpurified: 1/15;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
SNCA; synuclein, alpha; alpha-synuclein; alpha SYN; non-A4 component of amyloid; non-A beta component of AD amyloid
Entrez Gene ID
UniProt ID

Product Background


Pathway
Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; EGFR1 Signaling Pathway, organism-specific biosystem; Parkinsons disease, organism-specific biosystem;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Cuevas, C; Huenchuguala, S; et al. Glutathione Transferase-M2-2 Secreted from Glioblastoma Cell Protects SH-SY5Y Cells from Aminochrome Neurotoxicity. NEUROTOXICITY RESEARCH 27:217-228(2015).
Segura-Aguilar, J; Kostrzewa, RM; et al. Neurotoxin Mechanisms and Processes Relevant to Parkinson's Disease: An Update. NEUROTOXICITY RESEARCH 27:328-354(2015).

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