Specifications
Species Reactivity
Human; Fruit fly
Immunogen
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive)
Applications
Application Notes
WB: 1/10000, unpurified: 1/1000.00000 - 1/10000.00000; IHC-P: 1/150, unpurified: 1/15 to 1/300; Flow Cyt: 1/200, unpurified: 1/20; IP: 1/600, unpurified: 1/50; ELISA: 1 - 10 μg/ml; ICC/IF: 1/150, unpurified: 1/15;
Target
Alternative Names
SNCA; synuclein, alpha; alpha-synuclein; alpha SYN; non-A4 component of amyloid; non-A beta component of AD amyloid; NACP; alphaSYN;
Product Background
Antigen Description
May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.
Pathway
Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; EGFR1 Signaling Pathway, organism-specific biosystem; Parkinsons disease, organism-specific biosystem;
Citations
Publication ()
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COA
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