SARS-CoV-2 N protein (B.1.1.529/Omicron) was expressed in E. coli and fused a polyhistidine at the N-terminus. Mutants: P13L, E31del, R32del, S33del, R203K, G204R
Target
SARS-CoV-2 nucleocapsid
Nature
Recombinant
Tag/Conjugate
His
Alternative Names
SARS-CoV-2 NP; SARS-CoV-2 Nucleocapsid Protein
Format
Lyophilized
Buffer
50 mM PB, 500 mM NaCl, pH 7.0
Preservative
None
Introduction
Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. N protein packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
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