Native Goat CRP

Target

CRP

Nature

Native

Molecular Weight

23 kDa

Purity

> 95% as determined by SDS-PAGE

Format

Liquid

Buffer

10 mM Tris-HCl, pH 8.0, 150 mM NaCl, 1 mM EDTA

Preservative

0.09% sodium azide

Storage

Store at -20°C to -80°C

Introduction

C-reactive protein (CRP) is aprotein found in the blood, the levels of which rise in response toinflammation (i.e. C-reactive protein is an acute-phase protein). Itsphysiological role is to bind to phosphocholine expressed on the surface ofdead or dying cells (and some types of bacteria) in order to activate thecomplement system via the C1Q complex. CRP is synthesized by the liver inresponse to factors released by fat cells (adipocytes). It is a member of thepentraxin family of proteins. It is not related to C-peptide or protein C. C-reactiveprotein was the first pattern recognition receptor (PRR) to be identified.

Keywords

CRP; C-reactive protein