Anti-PF4 monoclonal antibody (DMAB35876)

Rabbit anti-Human PF4 monoclonal antibody for WB, IHC, IP Datasheet

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Specifications


Host Species
Rabbit
Clone
FQS8874
Species Reactivity
Human
Conjugate
Unconjugated

Applications


Application Notes
WB: 1:1,000 - 10,000; IHC: 1:100 - 250; IP: 1:10 - 100
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
PF4; platelet factor 4; chemokine (C X C motif) ligand 4; CXCL4; SCYB4; iroplact
Entrez Gene ID
UniProt ID

Product Background


Pathway
CXCR3-mediated signaling events, organism-specific biosystem; Cell surface interactions at the vascular wall, organism-specific biosystem; Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Common Pathway, organism-specific biosystem;

Citations


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References


Ahmad, S; Untch, B; et al. Functional IgG subtype of anti-heparin-PF4 antibodies is the principal mediator of HIT pathogenesis: Clinical and diagnostic implications.. BLOOD 100:79B-79B(2002).
Krane, V; Berger, M; et al. Antibodies to Platelet Factor 4-Heparin Complex and Outcome in Hemodialysis Patients with Diabetes. CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY 5:874-881(2010).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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