Anti-PF4 monoclonal antibody (DMAB35876)

Rabbit anti-Human PF4 monoclonal antibody for WB, IHC, IP Datasheet

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Specifications


Host Species
Rabbit
Clone
FQS8874
Species Reactivity
Human
Conjugate
Unconjugated

Applications


Application Notes
WB: 1:1,000 - 10,000; IHC: 1:100 - 250; IP: 1:10 - 100
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
PF4; platelet factor 4; chemokine (C X C motif) ligand 4; CXCL4; SCYB4; iroplact
Entrez Gene ID
UniProt ID

Product Background


Pathway
CXCR3-mediated signaling events, organism-specific biosystem; Cell surface interactions at the vascular wall, organism-specific biosystem; Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Common Pathway, organism-specific biosystem;

Citations


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References


McMeniman, WJ; Chard, RB; et al. Cardiac Surgery and Heparin Induced Thrombocytopaenia (HIT): A Case Report and Short Review. HEART LUNG AND CIRCULATION 21:295-299(2012).
Newman, PM; Chong, BH; et al. Heparin-induced thrombocytopenia: new evidence for the dynamic binding of purified anti-PF4-heparin antibodies to platelets and the resultant platelet activation. BLOOD 96:182-187(2000).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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