Anti-PF4 monoclonal antibody (DMAB35876)
Rabbit anti-Human PF4 monoclonal antibody for WB, IHC, IP
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WB: 1:1,000 - 10,000; IHC: 1:100 - 250; IP: 1:10 - 100
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
PF4; platelet factor 4; chemokine (C X C motif) ligand 4; CXCL4; SCYB4; iroplact
CXCR3-mediated signaling events, organism-specific biosystem; Cell surface interactions at the vascular wall, organism-specific biosystem; Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Common Pathway, organism-specific biosystem;
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Padmanabhan, A; Jones, CG; et al. Heparin-independent, PF4-dependent binding of HIT antibodies to platelets: implications for HIT pathogenesis. BLOOD 125:155-161(2015).
Kottke-Marchant, K; Bontempo, FA; et al. A positive in vitro assay is required to diagnose heparin-induced thrombocytopenia. MEDICAL CLINICS OF NORTH AMERICA 87:1215-+(2003).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.