Anti-PF4 polyclonal antibody [Biotin] (DPABY-408)

Goat Anti-Human PF4 polyclonal antibody for WB, ELISA(Det)

Specifications


Host Species
Goat
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
E. coli-derived recombinant human CXCL4/PF4 . Glu32-Ser101 Accession Number P02776
Conjugate
Biotin

Applications


Application Notes
Western Blot: 1 μg/mL; ELISA Capture: 2-8 μg/mL; ELISA Detection: 0.1-0.4 μg/mL
We recommend the following for sandwich ELISA (Capture - Detection):
DCABY-4093 - DPABY-408
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
PF4; platelet factor 4; PF-4; CXCL4; SCYB4; iroplact
Entrez Gene ID
UniProt ID

Product Background


Pathway
CXCR3-mediated signaling events; Cell surface interactions at the vascular wall; Chemokine receptors bind chemokines; Chemokine signaling pathway; Class A/1 (Rhodopsin-like receptors); Common Pathway; Cytokine-cytokine receptor interaction; Formation of F

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References


Pearson, MA; Nadeau, C; et al. Correlation of ELISA Optical Density With Clinical Diagnosis of Heparin-Induced Thrombocytopenia A Retrospective Study of 104 Patients With Positive Anti-PF4/Heparin ELISA. CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS 20:349-354(2014).
Visentin, GP; Scheidt, MJ; et al. Formation of antibodies reactive with PF4: Heparin complexes by children exposed to heparin.. BLOOD 94:16A-16A(1999).

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