Anti-PF4 monoclonal antibody (CABT-28753MH)
Mouse anti-Human PF4 monoclonal antibody for ELISA, FC, ICC/IF, IHC-P, WB
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Recombinant full length protein (Human)
WB: 0.5μg/ml; ICC/IF: 50μg/ml; ELISA: 0.1μg/ml;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
PF4; platelet factor 4; chemokine (C X C motif) ligand 4; CXCL4; SCYB4; short form
CXCR3-mediated signaling events, organism-specific biosystem; Cell surface interactions at the vascular wall, organism-specific biosystem; Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Common Pathway, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytoki
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Padmanabhan, A; Jones, C; et al. Platelet-activating HIT antibodies bind preferentially to PF4 treated platelets in the absence of heparin: implications for HIT pathogenesis. JOURNAL OF THROMBOSIS AND HAEMOSTASIS 12:68-68(2014).
Samake, H; Lechat, N; et al. Development of a disposable single test device to measure antibodies to heparin-PF4 complex as an aid to rapid diagnosis of HIT type II. THROMBOSIS AND HAEMOSTASIS :555-556(1999).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.