Magic™ Anti-FOXO1 (Phospho S319) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Peptide sequence around phosphorylation site of serine 319 (T-S-S(p)-N-A) derived from Human FOXO1.

Conjugate

Alternative Names

FOXO1; forkhead box O1; FKHR, forkhead homolog in rhabdomyosarcoma , FOXO1A; forkhead box protein O1; FKH1; forkhead box protein O1A; forkhead, Drosophila, homolog of, in rhabdomyosarcoma; FKHR; FOXO1A;

Entrez Gene ID

UniProt ID

Antigen Description

FKHR belongs to the forkhead family of transcription factors, which are characterized by a distinct forkhead domain. It may play a role in myogenic growth and di fferentiation. The mammalian DAF-16-like transcription factors, FOXO1, FKHRL1, and AFX, function as key regulators of insulin signaling, cell cycle progression, and apoptosis downstream of phosphoinositide 3-kinase.

Pathway

AKT phosphorylates targets in the nucleus, organism-specific biosystem; AKT-mediated inactivation of FOXO1A, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem; Adipogenesis, organism-specific biosystem; Angiopoietin receptor Tie2-mediated signaling, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; CXCR4-mediated signaling events, organism-specific biosystem;