Anti-FOXO1 monoclonal antibody (DMABT-H13783)

Mouse anti-Human FOXO1 monoclonal antibody for WB, IHC, ELISA Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2a
Clone
4B20
Species Reactivity
Human
Immunogen
FOXO1A (NP_002006, 452 a.a. ~ 555 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated

Target


Alternative Names
FOXO1; forkhead box O1; FKHR, forkhead homolog in rhabdomyosarcoma , FOXO1A; forkhead box protein O1; FKH1; forkhead box protein O1A
Entrez Gene ID
UniProt ID

Product Background


Pathway
AKT phosphorylates targets in the nucleus, organism-specific biosystem; AKT-mediated inactivation of FOXO1A, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem; Adipogenesis, organism-specific biosystem; Angiopoietin receptor Tie2-mediated signaling, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; CXCR4-mediated signaling events, organism-specific biosystem;

Citations


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References


Kerdiles, YM; Stone, EL; et al. Foxo Transcription Factors Control Regulatory T Cell Development and Function. IMMUNITY 33:890-904(2010).
Shu, TT; Zhu, YX; et al. AGEs Decrease Insulin Synthesis in Pancreatic beta-Cell by Repressing Pdx-1 Protein Expression at the Post-Translational Level. PLOS ONE 6:-(2011).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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