Specifications
Species Reactivity
Mouse; Human
Immunogen
Purified recombinant fragment of Human FOXO1A expressed in E. Coli.
Applications
Application Notes
WB: 1/500 - 1/2000; ELISA: 1/10000; IHC-P: 1/200 - 1/1000; ICC/IF: 1/200 - 1/1000;
Target
Alternative Names
FOXO1; forkhead box O1; FKHR, forkhead homolog in rhabdomyosarcoma , FOXO1A; forkhead box protein O1; FKH1; forkhead box protein O1A; forkhead, Drosophila, homolog of, in rhabdomyosarcoma; FKHR; FOXO1A;
Product Background
Antigen Description
Transcription factor which acts as a regulator of cell responses to oxidative stress. In the presence of KIRT1, mediates down-regulation of cyclin D1 and up-regulation of CDKN1B levels which are required for cell transition from proliferative growth to quiescence.
Pathway
AKT phosphorylates targets in the nucleus, organism-specific biosystem; AKT-mediated inactivation of FOXO1A, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem; Adipogenesis, organism-specific biosystem; Angiopoietin receptor Tie2-mediated signaling, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; CXCR4-mediated signaling events, organism-specific biosystem;
Citations
Publication ()
Have you cited DCABH-1893 in a publication?
Let us know and earn a reward for your research.
COA
Loading ......
