Human CK-MB Calibrator

Tag/Conjugate

Unconjugated

Alternative Names

CKB; creatine kinase, brain; CKBB; creatine kinase B-type; creatine kinase-B; creatine kinase B chain; B-CK

Format

Lyophilised

Buffer

100% Human Serum

Preservative

None

Storage

Stable to expiry date at 2°C to 8°C prior to reconstitution. Reconstituted stability of 5 days at 2°C to 8°C, , 8 hours at +25°C and 28 days at -20°C

Reconstitution

Open one vial of control serum very carefully, avoiding any loss of material, and reconstitute in exactly 1 ml of redistilled water. Close vial and leave to stand for 15 mins., dissolving contents completely by swirling or rotating gently.

Introduction

CreatineKinase MB consists of a dimer of nonidentical chains. With MM being the majorform in skeletal muscle and myocardium, MB existing in myocardium, and BBexisting in many tissues, especially brain. Creatine Kinase MB reversiblycatalyses the transfer of phosphate between ATP and various phosphogens. Thecreatine kinase isoenzymes play a central role in energy transduction intissues with large fluctuating energy demands such as skeletal muscle, heart,brain and spermatozoa.

Keywords

CKB; creatine kinase, brain; CKBB; creatine kinase B-type; creatine kinase-B; creatine kinase B chain; B-CK