Human type 3 Creatine Kinase MM Isoenzyme (DAG278)

Human type 3 Creatine Kinase MM Isoenzyme, recombinant protein from P. pastoris Datasheet

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Product Overview
CreatineKinase MM (CK-MM) Type 3 Isoenzyme Recombinant. Creatine Kinase MM isoenzymewith identical amino acid sequence to that of the native enzyme. CK-MM is a47 kDa dimeric protein comprised of 2 identical subunits. Purified in theenzymatically active fo
Nature
Recombinant
Tag/Conjugate
Unconjugated
Format
Purified, Liquid
Concentration
Lotspecific. Activity: Lot specific IU/mg total protein, One unit will transferone micromole of phosphate from creatine phosphate to ADP per minute at 37oC.Measured at 340nm as one equimolar amount of NADH produced by coupled reaction
Buffer
Tris-bufferedsaline (TBS), 10mM beta-mercaptoethanol, 50% glycerol, pH 7.0-7.5
Preservative
0.1% Sodium azide
Storage
2-8°C short term, -20°C long term
Introduction
The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family.
Antigen Description
Creatinekinase isoenzymes play a central role in energy transduction in tissues withlarge, fluctuating energy demands, such as skeletal muscle, heart, brain andspermatozoa.
Keywords
Creatine kinase-M; creatine kinase M chain; CKMM; M-CK; CKM; Creatine kinase M-type; creatine kinase, muscle; EC 2.7.3.2

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