Human type 1 Creatine Kinase MM Isoenzyme, recombinant protein from P. pastoris
CreatineKinase MM (CK-MM) Type I Isoenzyme. Recombinant full length Creatine KinaseMM isoenzyme without the C-terminal lysine on both subunits. CK-MM is a 47kDa dimeric protein comprised of 2 identical subunits of Type 1 sequence.Purified in the enzymatic
Lotspecific. Activity: Lot specific IU/mg total protein. One unit will transferone micromole of phosphate from creatine phosphate to ADP per minute at 37oC.Measured at 340nm as one equimolar amount of NADH produced by coupledreaction.
0.01MTris-HCl, 0.075M Sodium chloride, 10mM beta-mercaptoethanol, 50% glycerol, pH7.0 to 7.5
0.1% Sodium azide
2-8°C short term, -20°C long term
The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family.
Creatinekinase isoenzymes play a central role in energy transduction in tissues withlarge, fluctuating energy demands, such as skeletal muscle, heart, brain andspermatozoa.
Creatine kinase-M; creatine kinase M chain; CKMM; M-CK; CKM; Creatine kinase M-type; creatine kinase, muscle; EC 220.127.116.11