Active Rabbit PAI-1 ELISA Kit

Sample

Plasma

Intended Use

Rabbit PAI-1 activity assay is intended for the quantitative determination of active plasminogen activator inhibitor type 1 (PAI-1) in rabbit plasma. For research use only.

Storage

Store all kit components at 4°C upon arrival. Return any unused microplate strips to the plate pouch with desiccant. Reconstituted standard and primary may be stored at -80°C for later use. Do not freeze-thaw the standard and primary antibody more than once. Store all other unused kit components at 4°C. This kit should not be used beyond the expiration date.

Sensitivity

The minimun detectable dose (MOD) was determined by adding two standard deviations to the mean optical density value of twenty zero standard replicates (range OD450: 0.046-0.062) and calculationg the corresponding concentration. The MOD was 0.036ng/mL.

General Description

PAI-1 is involved in the regulation of the blood fibrinolytic system. Increased plasma levels of PAI-1 are implicated in the impairment of fibrinolytic function and may be associated with thrombotic diseases [1,2]. Levels of PAI-1 increase with age [3] and are elevated in conditions such as normal pregnancy [4] and sepsis [5].