Product Overview
MousePlasminogen Activator Inhibitor 1 (PAI-1) (wild type), Recombinant wasexpressed in Ecoli. Does not contain a fusion partner. Molecular weight:43kDa
Tag/Conjugate
Unconjugated
Concentration
2.2 mg/ml (OD280nm, E0.1%= 1.0)
Buffer
0.05M Sodiumacetate, 0.1M Sodium chloride, 1mM EDTA, pH 5.0
Storage
2-8°C short term, -20°C long term
Introduction
This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
Antigen Description
Plasminogen activator inhibitor-1(PAI-1) also known as endothelial plasminogen activator inhibitor or serpinE1 is a protein that in humans is encoded by the SERPINE1 gene. The otherPAI, plasminogen activator inhibitor-2 (PAI-2) is secreted by the placenta
Keywords
SERPINE1; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; PAI; PAI1; PAI-1; PLANH1; plasminogen activator inhibitor 1; serpin E1; endothelial plasminogen activator inhibitor; serine (or cysteine) proteinase i
Citations
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