HBV Surface Antigen (subtype adw ) (DAG2717)

HBV Surface Antigen (aa 1 - 144) (subtype adw ), recombinant protein from P. pastoris Datasheet

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Product Overview
HbsAg adw produced Pichia Pastoris, having a molecular weight of approximately 24. 0 kDa as shown on SDS-PAGE.
Nature
Recombinant
Tag/Conjugate
Unconjugated
Purity
Greater than 95. 0% as determined by(a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE Coomassie staining.
Format
Sterile Filtered solution containing 20mM Phosphat buffer, 154mM sodium chloride. Sterile Filtered yellowish liquid.
Storage
2-8°C short term, -20°C long term
Introduction
Hepatitis B Virus (HBV) infection inducesa disease state characterised by liver damage, inflammation and viralpersistence. Infection also increases the risk of hepatocellular carcinoma.HBV belongs to the Hepadnaviridae family of viruses. Its genome consists ofpartially double stranded circular DNA. The DNA is enclosed in anucleocapsid, or core antigen (HBcAg), which is surrounded by a sphericalenvelope (surface antigen or HBsAg). The core antigen shares its sequenceswith the e antigen (HBeAg) but no cross reactivity between the two proteinshas been observed. The HBV genome also encodes a DNA polymerase that alsoacts as a reverse transcriptase.

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