PIV type 1 Grade 2

Name: PIV type 1 Grade 2
SKU: DAG-H10371
Rating: 5 (1 reviews)

PIV type 1 Grade 2, native virus

COA

SDS

Datasheet

Summary

Nature

Native

Tag/Conjugate

Unconjugated

Buffer

NTE buffer (Sodium chloride, TRlS and EDTA)

Preservative

None

Storage

Store this antigen preparation frozen at:::;-70 °C . Repeated freezing and thawing should be avoided.

Introduction

Parainfluenza viruses belong to the genus Paramyxovirus of the family Paramyxoviridae. They are enveloped viruses with a single-strand RNA genome of negative polarity and range in diameter from 150 to 200 nm. Four types of parainfluenza viruses have been identified. Types 1 and 2 are major causes of laryngotracheo-bronchitis (croup), with greatest severity in children ages 2 to 4 years. Type 3 infection can also lead to croup but, most notably, is a major cause of infant bronchiolitis, pneumonia, and hospitalization. Infection from type 3 virus is most severe in infants less than 1 year old. Parainfluenza type 4 has been associated only with mild upper respiratory illness in adults and children.

Keywords

Group V ((-)ssRNA); Mononegavirales; Paramyxoviridae; Human parainfluenza viruses; HPIV3; Parainfluenza 3 virus; PIV3; Parainfluenza Type 2 and 3

Citations

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Documents

pdf COA

pdf SDS

pdf Datasheet

QA & Reviews

Customer Reviews

References

Quantitative RT Real Time PCR and indirect immunofluorescence for the detection of human parainfluenza virus 1, 2, 3

JOURNAL OF VIROLOGICAL METHODS

Authors: Terlizzi, Maria Elena; Bergallo, Massimiliano; Sidoti, Francesca; Sinesi, Franca; Vendrame, Rosangela; Gambarino, Stefano; Costa, Cristina; Cavallo, Rossana

Abstract

Human parainfluenza viruses (HPIVs) are distributed worldwide and are involved mainly in the pathogenesis of respiratory tract infections. The development and optimization of three quantitative reverse transcription real time polymerase chain reactions (RT Real Time Qt-PCRs) and an indirect immunofluorescence (IFA) for the detection and quantitation of HPIV-1, -2 and -3 in clinical samples are described. Efficiency, sensitivity, specificity, inter- and intra-assay variability and turnaround time of the two methods were compared. These assays have been validated on 131 bronchoalveolar lavage specimens. Based on the results obtained, the molecular methods represent a valid and rapid tool for clinical management and should be included in diagnostic panels aimed to evaluate suspected respiratory tract infections. (C) 2009 Elsevier B.V. All rights reserved.

New dodecanuclear phenylphosphonate-bridged Co(II) complexes

POLYHEDRON

Authors: Burkovskaya, Nataliya P.; Nikiforova, Marina E.; Kiskin, Mikhail A.; Lermontov, Anatoliy S.; Bogomyakov, Artem S.; Mironov, Vladimir S.; Dobrokhotova, Zhanna V.; Pekhnyo, Vasyl I.; Sidorov, Aleksei A.; Novotortsev, Vladimir M.; Eremenko, Igor L.

Abstract

New dodecanuclear phenylphosphonate-bridged Co(II) complexes [(mu(2)-THF)(5)(eta-HPiv)Co-12(mu(3)-OH)(4)(mu(6)-O3PPh)(4)(mu-Piv)(12)]center dot THF center dot 2C(6)H(6) (1 center dot THF center dot 2C(6)H(6)), [(mu(2)-THF)(6)Co-12(mu(3)-OH)(4)(mu(6)-O3PPh)(4)(mu-Piv)(12)]center dot 3THF (2 center dot 3THF) and [(mu(2)-Hmhp)(6)Co-12(mu(3)-OH)(4)(mu(6)-O3PPh)(4)(mu-Piv)(12)]center dot 6.5MeCN (3 center dot 6.5MeCN) have been synthesized by the reaction of the cobalt(II) pivalate polymer {Co(Piv)(2)}(n) (Piv is the pivalate anion), as a source of metal fragments containing cobalt(II) atoms, with potassium phenylphosphonate (K2PO3Ph) in the presence of neutral O-donor additional ligands like molecules of THF or 6-methyl-2-pyridone (Hmhp). The structures of the dodecanuclear complexes 1-3 were determined by using single-crystal X-ray diffraction data. The magnetic properties of the compounds showed that complexes 1 and 3 exhibit antiferromagnetic exchange interactions between the magnetic centers. The stability of compounds 1 and 3 were studied using thermogravimetric analysis. (C) 2011 Elsevier Ltd. All rights reserved.