Specifications
Species Reactivity
Human; Pig
Immunogen
Recombinant human IgG Fc fusion protein corresponding to pig PECAM1.
Applications
Application Notes
Flow Cytometry (10μl of the suggested working dilution (1:10-1:50) to label 100μl of lysed whole blood or 106 cells) & The optimal working dilution should be determined by the end user.
Target
Alternative Names
platelet/endothelial cell adhesion molecule; FLJ34100; CD31; FLJ58394; GPIIA"; adhesion molecule; PECA1; endoCAM; CD31 antigen; platelet endothelial cell adhesion molecule; CD31/EndoCAM; PECAM-1; PECAM-1, CD31/EndoCAM
Product Background
Antigen Description
The protein encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation.
Mouse monoclonal antibody raised against partial recombinant PECAM1.
Pathway
Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Cell surface interactions at the vascular wall, organism-specific biosystem; Formation of Platelet plug, organism-specific biosystem; Hemostasis, organism-specific biosystem; Integrin cell surface interactions, organism-specific biosystem
Citations
Publication ()
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COA
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