Specificity
Expressed on platelets and leukocytes and is primarily concentrated at the borders between endothelial cells. Isoform Long predominates in all tissues examined. Isoform Delta12 is detected only in trachea. Isoform Delta14-15 is only detected in lung. Isof
Tag/Conjugate
Unconjugated
SequenceSimilarities
Contains 6 Ig-like C2-type (immunoglobulin-like) domains.
Alternative Names
The Ig-like C2-type domains 2 and 3 contribute to formation of the complex with BDKRB2 and in regulation of its activity.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.
Antigen Description
The protein encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation. [provided by RefSeq, May 2010]
Function
protein binding;
Synonyms
PECAM1; platelet/endothelial cell adhesion molecule 1; CD31; PECA1; GPIIA; PECAM-1; endoCAM; CD31/EndoCAM; platelet endothelial cell adhesion molecule; CD31 antigen;
Citations
Publication ()
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COA
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