Specifications
Species Reactivity
Mouse; Human
Immunogen
Synthetic phosphopeptide derived from human CD31 around the phosphorylation site of tyrosine 713 (T-V-YP-S-E).
Applications
Application Notes
ICC/IF: 1/100 - 1/500; ELISA: 1/40000; WB: 1/500 - 1/1000
Target
Alternative Names
PECAM1; platelet/endothelial cell adhesion molecule; platelet endothelial cell adhesion molecule; CD31; CD31 antigen; Adhesion molecule; CD31; CD31 antigen; CD31 EndoCAM; Endocam; FLJ34100; FLJ58394; GPIIA; PECA1; PECA1_HUMAN; Pecam 1; PECAM 1 CD31 EndoCA
Product Background
Antigen Description
The protein encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation.
Pathway
Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Cell surface interactions at the vascular wall, organism-specific biosystem; Hemostasis, organism-specific biosystem; Integrin cell surface interactions, organism-specific biosystem; Leukocyte transendothelial migration, organism-specific biosystem; Leukocyte transendothelial migration, conserved biosystem; Malaria, organism-specific biosystem; Malaria, conserved biosystem; PECAM1 in
Citations
Publication ()
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COA
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