Recombinant protein (11.5 kDa) manufactured in E. coli. Contains the Immunoglobulin-like domain DIII of Dengue virus serotype 2 (DENV2) envelope protein. Protein contains a His-tag and has an approximate pI of 6.7-7.
DENV Envelope protein
DENV, DENV type 2, DENV E Protein, DENV DIII Envelope Protein, DENV type 2 E Protein DIII
> 95% as determined by SDS-PAGE
20mM Carbonate buffer pH9.6
Upon arrival, store at -80°C.
Dengue virus envelope protein is a major structural glycosylated protein that forms homodimers on the virion surface. Each envelope protein is organised into three domains, the central domain DI, the dimerization domain DII and an immunoglobulin-like domain DIII. Envelope protein DIII is reported to be a receptor-recognition and binding domain, and an important target for the human immune response. The DIII domain is highly immunogenic and elicits the production of neutralising antibodies against the wild-type virus.
DENV; DENV type 2; DENV E Protein; DENV DIII Envelope Protein; DENV type 2 E Protein DIII