DENV Envelope protein 3 (DAG2714)

DENV Envelope protein 3, recombinant protein from E. coli

Product Overview
The E. coli derived recombinant 28 kDa protein is genetically engineered peptide which is derived from Dengue Type-3 Envelope. This region also contains a common antigen for Dengue type 1, 2 and 4. The sequence is from Dengue virus type 3 strain C0360/94,
Nature
Recombinant
Tag/Conjugate
Unconjugated
Procedure
None
Purity
Protein is > 95% pure as determined by 10% PAGE (coomassie staining).
Preservative
None
Storage
2-8°C short term, -20°C long term
Introduction
Dengue (DF) and dengue hemorrhagic fever (DHF) are caused by one of four closely related, but antigenically distinct, virus serotypes (DEN-1, DEN-2, DEN-3, and DEN-4), of the genus Flavivirus. Infection with one of these serotypes provides immunity to only that serotype for life, so persons living in a dengue-endemic area can have more than one dengue infection during their lifetime. DF and DHF are primarily diseases of tropical and sub tropical areas, and the four different dengue serotypes are maintained in a cycle that involves humans and the Aedes mosquito
Antigen Description
Caused by one of four closely related virus serotypes of the genus Flavivirus, family Flaviviridae, each serotype is sufficiently different that there is no cross-protection and epidemics caused by multiple serotypes (hyperendemicity) can occur. In cell culture experiments and mice Morpholino antisense oligos have shown specific activity against Dengue virus.
Keywords
Dengue Type 2; Dengue Type 2, Envelope (E); DENE; DENE E; DEN-2; Flaviviridae; Flavivirus; DENV P3; Dengue virus P3; P3; Dengue Virus Envelope Protein-3; Protein-3

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