DENV type 4 Envelope protein [His] (DAG459)

DENV type 4 Envelope protein [His], recombinant protein from E. coli

Product Overview
Recombinant Dengue Type-4 Envelope contains a common antigen for Dengue type 1, 2 and 3 and contains a 6-His fusion partner, was expressed in E. coli. Recombinant Dengue Type-4 Envelope can reacts strongly with Dengue IgG, and can reacts with Dengue IgM i
Nature
Recombinant
Tag/Conjugate
His
Procedure
None
Purity
> 95% pure (10% PAGE (Coomassie)). Proprietary chromatographic technique
Format
Purified, Liquid
Concentration
1.78 mg/ml
Buffer
PBS, pH 7.4
Preservative
None
Storage
2-8°C short term, -20°C long term
Introduction
Dengue virus (DENV) in one of four serotypes is the cause of dengue fever. It is a mosquito-borne single positive-stranded RNA virus of the family Flaviviridae; genus Flavivirus. All four serotypes can cause the full spectrum of disease. Its genome is about 11000 bases that codes for three structural proteins, capsid protein C, membrane protein M, envelope protein E; seven nonstructural proteins, NS1, NS2a, NS2b, NS3, NS4a, NS4b, NS5; and short non-coding regions on both the 5' and 3' ends. Further classification of each serotype into genotypes often relates to the region where particular strains are commonly found or were first found.
Antigen Description
Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as an homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes.
Keywords
DENV; Dengue Virus Envelope Protein; DENV Envelope Protein; Dengue virus

Citations


Have you cited DAG459 in a publication? Let us know and earn a reward for your research.

Customer Reviews


Write a review, share your experiences with others and get rewarded !
Product Name Cat. No. Applications Host Species Datasheet Price Add to Basket
Product Name Cat. No. Applications Host Species Datasheet Price Add to Basket

Online Inquiry

Name:
Phone: *
E-mail Address: *
Service & Products Interested: *
Project Description:
Verification Code: * Please input "diagnostics" as verification code.

Online Inquiry

  Interested in larger quantities ? request a quote!
  Protocol may be improved. Please feel free to contact us to obtain the latest version.!

Ordering Information

Payment methods we support:
Invoice / Purchase Order
Credit card

OUR PROMISE TO YOU Guaranteed product quality expert customer support

Inquiry Basket