M. tuberculosis H37Rv is cultured in liquid medium and harvested by centrifugation
Nature
Native
Format
Lyophilized powder
Preservative
None
Storage
Store at -20°C for 1 years
Introduction
Mycobacterium tuberculosis (M. tb) is a species of pathogenic bacteria in the family Mycobacteriaceae and the causative agent of tuberculosis. First discovered in 1882 by Robert Koch, M. tuberculosis has an unusual, waxy coating on its cell surface primarily due to the presence of mycolic acid. This coating makes the cells impervious to Gram staining, and as a result, M. tuberculosis can appear weakly Gram-positive. The physiology of M. tuberculosis is highly aerobic and requires high levels of oxygen. Primarily a pathogen of the mammalian respiratory system, it infects the lungs. The most frequently used diagnostic methods for tuberculosis are the tuberculin skin test, acid-fast stain, culture, and polymerase chain reaction.
Keywords
Mycobacterium tuberculosis; TB; H37Rv
Inactivation
Heat inactivated (80°C, 1h)
Citations
Publication ()
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