Human tuberculosis (TB) antibody (IgM) ELISA Kit

Name: Human tuberculosis (TB) antibody (IgM) ELISA Kit
SKU: DEIA386
Rating: 5 (1 reviews)

Regulatory status: For research use only, not for use in diagnostic procedures.

COA

SDS

Datasheet

Summary

Sample

Serum

Species Reactivity

Human

Detection Method

iELISA

Intended Use

For the qualitative determination of human tuberculosis (TB) antibody (IgM) concentrations in serum, plasma.

Contents of Kit

1.Coated assay plate, 1(96 wells)
2.Negative Control, 1 x 0.5 ml
3.Positive Control, 1 x 0.5 ml
4.Sample Diluent, 1 x 20 ml
5.HRP-conjugate, 1 x 12 ml
6.Wash Buffer (30 x concentrate), 1 x 20 ml
7.Substrate A, 1 x 5 ml
8.Substrate B, 1 x 5 ml
9.Stop Solution, 1 x 5 ml
10.Adhesive Strip (For 96 wells), 4
11.Instruction manual, 1

Storage

Unopened kit: Store at 2 - 8°C. Do not use the kit beyond the expiration date.
Opened kit: May be stored for up to one month at 2 - 8° C.
*Provided this is within the expiration date of the kit.

Precision

Intra-assay Precision (Precision within an assay): CV%<15%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays): CV%<15%
Three samples of known concentration were tested in twenty assays to assess.

Citations

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Documents

pdf COA

pdf SDS

pdf Datasheet

QA & Reviews

Customer Reviews

References

A study on the relationship between air pollution and pulmonary tuberculosis based on the general additive model in Wulumuqi, China

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Authors: Yang, Jiandong; Zhang, Mengxi; Chen, Yanggui; Ma, Li; Yadikaer, Rayibai; Lu, Yaoqin; Lou, Pengwei; Pu, Yujiao; Xiang, Ran; Rui, Baolin

Abstract

Objective: This study aimed to explore the impact of atmospheric pollutants on the incidence of tuberculosis (TB), and provide new ideas for the prevention and control of TB in the future. Methods: It explored the relationship between air pollutants and meteorological factors, as well as between air pollutants and heating through Spearman correlation analysis and rank sum test. Additionally, it analyzed the relationship between air pollutants and TB incidence using the general additive model. Statistical analysis results at the p < 0.05 level were considered significant. Results: Three months after exposure to air pollutants (PM2.5, SO2, NO2, and CO) TB incidence increased. However, TB incidence increased 9 months after exposure to PM10. The single pollutant model showed when concentrations of PM2.5, PM10, SO2, NO2, CO, and O-3 increased by 1 mg/m(3) (or 1 mg/m(3)), the number of TB cases increased by 0.09%, 0.08%, 0.58%, 0.42%, 6.9%, and 0.57%, respectively. The optimal multi-pollutant model was a two-factor model (PM10 + NO2). Conclusion: Air pollutants including PM2.5, PM10, SO2, NO2, CO, and O-3 increased the risk of TB. Few studies have been conducted in this area of research, especially regarding the mechanism. The results of this study should contribute to the understanding of TB incidence and prompt additional research. (C) 2020 The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases.

Exploring MDR-TB Inhibitory Potential of 4-Aminoquinazolines asMycobacterium tuberculosis N-Acetylglucosamine-1-Phosphate Uridyltransferase (GlmU(MTB)) Inhibitors

CHEMISTRY & BIODIVERSITY

Authors: Patel, Harun M.; Palkar, Mahesh; Karpoormath, Rajshekhar

Abstract

Drug resistance tuberculosis is one of the challenging tasks that dictates the desperate need for the development of new antitubercular agents which operatevianovel modes of action. Here, we are reporting on 4-aminoquinazolines asM. tuberculosis N-acetylglucosamine-1-phosphate uridyltransferase (GlmU(MTB)) inhibitors to overcome the problem of the MDR-TB. Amongst the synthesized compounds, two of them were observed to be the effective compounds of the series (IC50=6.4 mu M (H37Rv), MIC=25 mu M (MDR-TB) and IC50=2.9 mu M (H37Rv), MIC=6.25 mu M (MDR-TB), respectively).