M. tuberculosis H37Ra is cultured in liquid medium and harvested by centrifugation
Nature
Native
Format
Lyophilized powder
Preservative
None
Storage
Store at -20°C for 1 years
Introduction
Mycobacterium tuberculosis (M. tb) is a species of pathogenic bacteria in the family Mycobacteriaceae and the causative agent of tuberculosis. First discovered in 1882 by Robert Koch, M. tuberculosis has an unusual, waxy coating on its cell surface primarily due to the presence of mycolic acid. This coating makes the cells impervious to Gram staining, and as a result, M. tuberculosis can appear weakly Gram-positive. The physiology of M. tuberculosis is highly aerobic and requires high levels of oxygen. Primarily a pathogen of the mammalian respiratory system, it infects the lungs. The most frequently used diagnostic methods for tuberculosis are the tuberculin skin test, acid-fast stain, culture, and polymerase chain reaction.
Keywords
Mycobacterium tuberculosis; TB; H37Ra
Inactivation
Heat inactivated (80°C, 1h)
Citations
Publication ()
Have you cited DAG-WT751 in a publication? Let us know and earn a reward for your research.
Q: If it is suitable for use as a control in vaccine design, could you please provide guidance on its dilution for injection in mice? Additionally, what would be a recommended dose to use?
A: To reconstitute the Inactivated M. tuberculosis H37Ra (DAG-WT751) product, we recommend adding 1 mL of sterile saline to achieve a concentration of approximately 4x10^9 CFU/mL. For vaccine design and injection in mice, a dose of 10^6–10^8 CFU is typically recommended. However, the exact dosage should be determined by the end user based on their specific experimental design.
Customer Reviews
My Review for Inactivated M.tuberculosis H37Ra
Creative Diagnostics products are for RESEARCH USE ONLY, please make sure your review is research based.
Required fields are marked with *
Terms and conditions:
We will select high-quality review customers and offer a $30 coupon for your next purchase.
All product reviews must be submitted in the English language.
Creative Diagnostics will not share any personal information of applicants, and all information will be treated with strict confidentiality and will not be sold or disclosed to a third party.
COA
Publication 
Loading ......
