Sulfonamides [HRP]

Name: Sulfonamides [HRP]
SKU: DAGA-211H
Rating: 5 (1 reviews)

Sulfonamides HRP Conjugated, Synthetic antigen for ELISA

COA

SDS

Datasheet

Summary

Nature

Synthetic

Tag/Conjugate

HRP

Alternative Names

Sulfonamides; 1; 3-Difluoro-5-methylsulfonylbenzene; 3; 5-Difluoro-1-(methylsulfonyl)benzene; 2-Chloro-1-fluoro-4-methylsulfonylbenzene; 3-Chloro-4-fluoro-1-(methylsulfonyl)benzene; N-(4-Methoxybenzyl)-1; 3-propanesultam; N-(4-Methoxybenzyl)-N-methylbenzenes

Format

Liquid

Concentration

Batch dependent - please inquire should you have specific requirements.

Buffer

0.01M pH7.4 PBS

Preservative

None

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Antigen Description

Sulfonamide or sulphonamide is the basis of several groups of drugs. The original antibacterial sulfonamides (sometimes called sulfa drugs or sulpha drugs) are synthetic antimicrobial agents that contain the sulfonamide group. Some sulfonamides are also devoid of antibacterial activity, e.g., the anticonvulsant sultiame. The sulfonylureas and thiazide diuretics are newer drug groups based on the antibacterial sulfonamides.

Keywords

Citations

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Documents

pdf COA

pdf SDS

pdf Datasheet

QA & Reviews

Customer Reviews

References

Transition-Metal-Free Tandem Cyclization/N-Arylation Reaction: A Method To Access Biaryl Sultam Derivatives via a Diradical Pathway

ORGANIC LETTERS

Authors: Thorat, Vijaykumar H.; Hsieh, Jen-Chieh; Cheng, Chien-Hong

Abstract

A novel procedure for the transition-metal-free tandem cyclization/N-arylation reaction sequence of an aryne with a 1,2,3,4-benzothiatriazine-1,1-dioxide is reported. This reaction goes through the intramolecular homolytic cyclization to generate an N-H biaryl sultam intermediate, which enables aryne insertion to access diversely functionalized biaryl sultam derivatives with high yields. The mechanism study indicates that homolytic cyclization is executed by a diradical species, initiated from the thermal decomposition of 1,2,3,4-benzothiatriazine-1,1-dioxide to release a nitrogen molecule.

Synthetic approaches and applications of sulfonimidates

ORGANIC & BIOMOLECULAR CHEMISTRY

Authors: Matos, Priscilla Mendonca; Stockman, Robert A.

Abstract

This review article explores the synthesis of the organosulfur(vi) species named sulfonimidates, focusing on their synthesis from sulfur(ii), sulfur(iv) and sulfur(vi) reagents, and investigates their recent resurgeance in interest as intermediates to access other important organosulfur compounds. Sulfonimidates have been utilized as precursors for polymers, sulfoximine and sulfonimidamide drug candidates and as alkyl transfer reagents.