Sulfonamides rapid test strip (Tissue) (DTS1018L)

Regulatory status: For research use only, not for use in diagnostic procedures.

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Intended Use
Sulfonamides rapid test strip is developed for rapid test of sulfonamides contamination in tissue.
The kit can be stored at room temperature (2-30°C). The test kit is stable through the expiration date marked on the foil pouch. DO NOT FREEZE. Do not store the test kit in direct sunlight.
The sensitivity of sulfonamides in tissue is 60 ppb.
General Description
Sulfonamide or sulphonamide is the basis of several groups of drugs. The original antibacterial sulfonamides (sometimes called sulfa drugs or sulpha drugs) are synthetic antimicrobial agents that contain the sulfonamide group. Some sulfonamides are also devoid of antibacterial activity, e.g., the anticonvulsant sultiame. The sulfonylureas and thiazide diuretics are newer drug groups based on the antibacterial sulfonamides.


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Sulfonamide degradation and metabolite characterization in submerged membrane photobioreactors for livestock excreta treatment


Authors: Lee, Jae-Cheol; Jang, Jae Kyung; Kim, Hyun-Woo

Residual veterinary antibiotics have been detected in livestock wastewater treatment plants. Despite the long retention time, antibiotic treatment efficiency has shown clear limitations. In this study, we evaluated submerged membrane photobioreactors (SMPBR) during sulfonamide antibiotic-containing livestock wastewater treatment under mixotrophic and photoautotrophic conditions. The results showed that microalgal sulfur degradation and consumption under mixotrophic conditions accelerated the biomass concentration increase to 2800 mg VSS/L compared to the 1800 mg VSS/L measured under photoautotrophic conditions. Although microalgal metabolites, such as soluble microbial products and extracellular polymeric substances, might cause membrane fouling in the SMPBR, we proved that microalgae could remove sulfonamide and release degradation-associated sulfur, along with nitrogen and phosphorus. Moreover, this study confirms the statistical correlation between metabolites and sulfonamides. In summary, the results of this study provide promising insights into antibiotic-containing livestock wastewater treatment. (C) 2020 Elsevier Ltd. All rights reserved.

Understanding Antibiotic Residues and Pathogens Flow in Wastewater from Smallholder Pig Farms to Agriculture Field in Ha Nam Province, Vietnam


Authors: Phuc Pham-Duc; Hung Nguyen-Viet; Toan Luu-Quoc; Cook, Meghan A.; Phuong Trinh-Thi-Minh; Payne, Dave; Trang Dao-Thu; Grace, Delia; Dang-Xuan, Sinh

Background: Contact with livestock wastewater on farms and in communities can pose a risk to human and animal health. Methods: This cross-sectional study was conducted in 180 households and 24 pig farms (96 wastewater samples) to explore information about pig production, livestock waste management, antibiotic use, and to analyze antibiotic residues and microbial contamination, respectively. Results: Of the 120 households raising pigs, biogas systems were the most commonly used to treat animal waste (70%), followed by compositing (19%), and the remaining respondents discharged waste directly into drains or ponds (11%). The majority of respondents (78%) used antibiotics to treat and prevent disease in pigs, but 32% of them did not know of any disadvantages of antibiotic abuse. ELISA assays were performed on half of the wastewater samples (n = 48), demonstrating that residues of flouroquinolones and sulfonamides were present in 6.3% (3/48) and 22.9% (11/48) of tested samples, respectively. The average residual level of sulfamethazine was 27.8 ug/l. Further,E. coliconcentrations exceeding regulatory levels in Vietnam were found in nearly all samples.Salmonellaspp. was also found in 57.3% of samples, though prevalence rates varied across the different sites. Finally,G. lambliawas found in 8.4% of samples, andC. parvumwas found in 5.2% of samples. Conclusions: This study suggests that livestock wastewater carried potential harmful pathogens and antibiotic residues that could come into contact with humans in the community. Thus, appropriate operation and application of livestock wastewater treatment (such as biogas or composting) and management should be a continued focused.

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