Rotavirus Positive Sample (DAG-H10377)

Nature
Native
Tag/Conjugate
Unconjugated
Preparation
A cellular monolayer of MA104 cells is infected with Rotavirus particles. Cell culture lysate is harvested and clarified.
Procedure
None
Preservative
None
Storage
Store this preparation at 2°C to 8°C.
Introduction
Rotavirus is the most common cause of severe diarrhea among infants and young children. It is a genus of double-stranded RNA virus in the family Reoviridae. Nearly every child in the world has been infected with rotavirus at least once by the age of five. Immunity develops with each infection, so subsequent infections are less severe; adults are rarely affected. There are five species of this virus, referred to as A, B, C, D, and E. Rotavirus A, the most common species, causes more than 90% of rotavirus infections in humans.
Antigen Description
This product contains inactivated rotavirus in storage buffer.
Keywords
Rotavirus
Inactivation
Rotavirus antigen is inactivated using UV irradiation. This procedure is effective primarily by damaging viral RNA. Rotavirus inactivation is assessed using a double-passage assay in tissue culture. Rotavirus antigen is inoculated onto an MA104 cell monol

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Product Name Cat. No. Applications Host Species Datasheet Price Add to Basket
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References


Nakagomi, T; Nakagomi, O; et al. A critical review on a globally-licensed, live, orally-administrable, monovalent human rotavirus vaccine: Rotarix. EXPERT OPINION ON BIOLOGICAL THERAPY 9:1073-1086(2009).
Souza, M; Costantini, V; et al. Human norovirus-like particle vaccine adjuvanted with ISCOM or mLT induces cytokine and antibody responses and protection to the homologous GII.4 human norovirus in a gnotobiotic pig disease model. VACCINE 25:8448-8459(2007).

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