Tag/Conjugate
Unconjugated
Storage
Store this preparation at 2°C to 8°C.
Introduction
Rotavirus is the most common cause of severe diarrhea among infants and young children. It is a genus of double-stranded RNA virus in the family Reoviridae. Nearly every child in the world has been infected with rotavirus at least once by the age of five. Immunity develops with each infection, so subsequent infections are less severe; adults are rarely affected. There are five species of this virus, referred to as A, B, C, D, and E. Rotavirus A, the most common species, causes more than 90% of rotavirus infections in humans.
Antigen Description
This product contains inactivated rotavirus in storage buffer.
Inactivation
Rotavirus antigen is inactivated using UV irradiation. This procedure is effective primarily by damaging viral RNA. Rotavirus inactivation is assessed using a double-passage assay in tissue culture. Rotavirus antigen is inoculated onto an MA104 cell monol
Citations
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Rivero, Z; Maldonado, A; et al. Prevalence of Enteroparasites, Rotavirus and Adenovirus in Apparently Healthy Children. KASMERA 37:62-73(2009).
Li, RC; Li, YP; et al. Reactogenicity and safety of a liquid human rotavirus vaccine (RIX4414) in healthy adults, children and infants in China Randomized, double-blind, placebo-controlled phase I studies. HUMAN VACCINES & IMMUNOTHERAPEUTICS 9:1638-1642(2013).
COA
Certificate of Analysis![Recombinant Rotavirus VP6 protein [His] (DAGC411)](http://img2.creative-diagnostics.com/productimages/DAGC411-1.png)
