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Introduction
The genus rotavirus belongs to the Reoviridae family of viruses. Rotaviruses are non-enveloped, double-stranded RNA (dsRNA) viruses, capable of infecting animals, birds and humans. In the mature virion, a complex triple-layered viral capsid surrounds a genome, composed of eleven segments of dsRNA. These RNA segments code for 6 structural and 6 non-structural proteins (CDC). Rotavirus are classified according to the serological reactivity and genetic variability of the structural VP6 protein. Currently, eight species of rotavirus are recognised and are referred to as groups A-H. Group A rotaviruses are the most common cause of human disease, but group B and C rotaviruses have also been found to infect humans.
Keywords
Rotavirus; Rotavirus VP6; Rotavirus VP6 Protein
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